A normal DNA sequence is 5′-GTA GCA TCA CCA-5′.If the DNA sequence mutated to 5′-GTA GCA TTC ACC A-3′, how would the peptide sequence be affected?
A) All amino acids downstream of the mutation would be changed.
B) The peptide would not be synthesized.
C) An Arg would replace an His.
D) A stop would replace a Trp.
E) No change would occur.

Question

Quizplus · Accepted Answer

The mutation introduces an extra nucleotide, causing a frameshift mutation. This changes the reading frame, altering all downstream amino acids.

A Normal DNA Sequence Is 5′-GTA GCA TCA CCA-5′