Tamoxifen is a drug used to prevent the recurrence of certain types of breast cancers that require estrogen to grow.Tamoxifen binds to the active site of the estrogen receptor protein, preventing estrogen from binding to the enzyme.Once Tamoxifen binds to the protein, the protein is permanently deactivated.Which descriptions BEST fits Tamoxifen?
A) Tamoxifen is an irreversible, noncompetitive inhibitor.
B) Tamoxifen is a reversible, noncompetitive inhibitor.
C) Tamoxifen is an irreversible, competitive inhibitor.
D) Tamoxifen is a reversible, competitive inhibitor.
E) Tamoxifen is not an inhibitor.

Question

Quizplus · Accepted Answer

Tamoxifen acts by binding to the estrogen receptor's active site, directly competing with estrogen, and it does so in a manner that permanently alters the receptor's ability to bind estrogen, making it an irreversible, competitive inhibitor.

Tamoxifen Is a Drug Used to Prevent the Recurrence of Certain