Why doesn't denaturation affect the primary structure of a protein?
A) Actually, denaturation does hydrolyze amino acids.
B) Peptide bonds are higher energy bonds than other interactions.
C) Peptide bonds are stronger than other interactions.
D) Peptide bonds are weaker than other interactions.
E) Peptide bonds cannot be broken under any circumstances.

Question

Quizplus · Accepted Answer

Denaturation affects the secondary, tertiary, and quaternary structures of proteins by disrupting the hydrogen bonds, hydrophobic interactions, and disulfide bridges that maintain these structures. However, the primary structure, which is the sequence of amino acids held together by peptide bonds, remains intact because peptide bonds are strong covalent bonds that are not broken by conditions that cause denaturation.

Why Doesn't Denaturation Affect the Primary Structure of a Protein