Each of the following is true about cytochrome c in apoptosis except A)It is released from mitochondria. B)It stimulates Ca²⁺ release from mitochondria. C)It stimulates Ca²⁺ release from the endoplasmic reticulum. D)It activates Rheb. E)It associates with Apaf1 to form an apoptosome.

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Quizplus · Accepted Answer

Cytochrome c, when released from mitochondria, plays a crucial role in apoptosis by associating with Apaf1 to form an apoptosome, but it does not activate Rheb. Rheb is involved in the mTOR signaling pathway, which is distinct from the apoptotic pathways directly involving cytochrome c.

Each of the Following Is True About Cytochrome C in Apoptosis