Which of the following is the correct order of steps in the EGF-cAMP signaling pathway?
A)ligand binding-G-protein activation- adenylyl cyclase activation-cAMP production-protein kinase A activation
B)ligand binding-protein kinase A activation-G-protein activation-adenylyl cyclase activation-cAMP production
C)G-protein activation-ligand binding-adenylyl cyclase activation-cAMP production-protein kinase A activation.
D)ligand binding-G-protein activation-adenylyl cyclase activation-cAMP production-protein kinase A activation
E)ligand binding-adenylyl cyclase activation-G-protein activation-cAMP production-protein kinase A activation

Question

Quizplus · Accepted Answer

The correct order is: ligand binding leads to G-protein activation, which then activates adenylyl cyclase. This results in cAMP production, which subsequently activates protein kinase A.

Which of the Following Is the Correct Order of Steps