While characterizing the activities of several neurons,you find a neuron with the following properties: (1)When stimulated,the neuron fails to release neurotransmitters into the synaptic cleft.
(2)Microinjection of calcium ions calcium ions has no effect on the neuron.(In other neurons such microinjection stimulates the t-SNARE and v-SNARE complex interaction that promotes neurotransmitter secretion.)
The abnormality in this neuron is most likely associated with the function of
A)the vesicle membranes.
B)acetylcholinesterase.
C)synaptotagmin.
D)GABA receptors.
E)gap junctions.

Question

Quizplus · Accepted Answer

Synaptotagmin acts as a calcium sensor and is crucial for the calcium-dependent triggering of neurotransmitter release. The failure to release neurotransmitters upon stimulation and the lack of response to calcium ion microinjection suggest a problem with the mechanism that senses calcium to trigger neurotransmitter release, which is the role of synaptotagmin.

While Characterizing the Activities of Several Neurons,you Find a Neuron