A drug that specifically inhibits voltage-gated calcium channels would most directly inhibit
A)depolarization of nerve cell membranes.
B)repolarization after depolarization of nerve cell membranes.
C)hyperpolarization of nerve cell membranes.
D)presynaptic neurotransmitter release.
E)postsynaptic receptor signal response.

Question

Quizplus · Accepted Answer

Voltage-gated calcium channels are crucial for the release of neurotransmitters from presynaptic terminals. When an action potential reaches the terminal, these channels open, allowing calcium to enter the cell. This influx of calcium triggers the fusion of neurotransmitter-containing vesicles with the presynaptic membrane, leading to neurotransmitter release into the synaptic cleft. Inhibiting these channels would directly impair this process, reducing or preventing neurotransmitter release.

A Drug That Specifically Inhibits Voltage-Gated Calcium Channels Would Most