Base-modifying chemicals such as aflatoxin B₁or nitrosoguanidine cause mutations by A)increasing the likelihood of depurination. B)causing double-stranded breaks in the DNA sugar-phosphate backbone. C)causing mispairing during DNA replication. D)causing pyrimidine dimers. E)increasing the likelihood of depurination or causing mispairing during DNA replication.

Question

Quizplus · Accepted Answer

Base-modifying chemicals like aflatoxin and nitrosoguanidine induce mutations primarily by altering the structure of the DNA bases, which can increase the likelihood of depurination or cause mispairing during DNA replication. These alterations can lead to incorrect base pairing and ultimately mutations.

Base-Modifying Chemicals Such as Aflatoxin B1 or Nitrosoguanidine Cause Mutations

Base-Modifying Chemicals Such as Aflatoxin B₁or Nitrosoguanidine Cause Mutations