In hereditary nonpolyposis colon cancer,mutations in MutS and MutH proteins result in the accumulation of mutations caused by
A)mismatched base pairs.
B)structurally damaged bases.
C)double-stranded DNA breaks.
D)thymine dimers.
E)DNA recombination.

Question

Quizplus · Accepted Answer

Mismatch repair proteins, such as MutS and MutH, are involved in correcting errors that occur during DNA replication, such as mismatched base pairs. In hereditary nonpolyposis colon cancer (HNPCC), mutations in these proteins lead to an accumulation of replication errors, contributing to cancer development.

In Hereditary Nonpolyposis Colon Cancer,mutations in MutS and MutH Proteins