Although MCF-10A breast cancer cells grow well on Matrigel-coated culture dishes,the cells will form cysts of polarized cells that produce milk only when

Question

Quizplus · Accepted Answer

The formation of cysts of polarized cells that produce milk in MCF-10A breast cancer cells requires a 3D environment, which can be achieved when the Matrigel layer is thick enough. This 3D culture environment allows the cells to organize and differentiate in a manner that closely mimics their natural structure and function in tissue.

Although MCF-10A Breast Cancer Cells Grow Well on Matrigel-Coated Culture