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Human Erythrocytes Have No Mitochondria

Question 59

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Human erythrocytes have no mitochondria.The rare inherited metabolic disorder that results from pyruvate kinase deficiency is particularly destructive to erythrocytes and causes hemolytic anemia.
a)Suggest a reason for increased erythrocyte death in the presence of pyruvate kinase deficiency.
b)Suggest a reason for the low incidence of mutations in human glycolytic enzymes.

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a)Erythrocytes make virtually all ATP th...

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