When a mouse cell and a human cell with different cell-surface protein markers are fused using polyethylene glycol (PEG)and immediately placed at 0°C,what would you expect happens to the mouse and human marker proteins?
A)Both the mouse and human marker proteins will rapidly disperse evenly throughout the fused membrane.
B)Only the mouse cell marker proteins will disperse throughout the fused membrane; the human marker proteins will remain confined to the original human region of the fused membrane.
C)The mouse and human markers will migrate to opposite poles of the fused membrane.
D)The mouse and human markers will migrate little and remain confined to their original membrane regions.
E)Both mouse and human markers will be endocytosed by the fused cell and destroyed in the fused cell.

Question

Quizplus · Accepted Answer

At 0°C, the mobility of proteins within the membrane is greatly reduced due to the decreased fluidity of the lipid bilayer, causing both mouse and human marker proteins to remain largely confined to their original regions of the membrane.

When a Mouse Cell and a Human Cell with Different