FRAP has revealed that some proteins move in cell membranes much slower than they move in reconstituted liposomes.Which of the following could account for limited mobility of proteins in cell plasma membranes?
A)association with other proteins in a large complex.
B)association with lipid rafts.
C)anchorage to the extracellular matrix.
D)anchorage to the cell cytoskeleton.
E)All could limit protein mobility.

Question

Quizplus · Accepted Answer

All the options listed (association with other proteins in a large complex, association with lipid rafts, anchorage to the extracellular matrix, and anchorage to the cell cytoskeleton) can contribute to limiting the mobility of proteins in cell plasma membranes. These factors can restrict the free diffusion of membrane proteins by tethering them to specific locations, causing them to aggregate, or by altering the local lipid environment.

FRAP Has Revealed That Some Proteins Move in Cell Membranes