Enhancers Can Be Identified by

Enhancers can be identified by

A) cloning a region of DNA with the putative enhancer in a reporter plasmid and demonstrating an increase in gene expression when the construct is introduced into a eukaryotic cell.
B) sequence comparison with promoter sequences that are already known.
C) introducing two separate pieces of DNA into a eukaryotic cell.One is a fragment of DNA with the putative enhancer and the other is a plasmid that contains a reporter gene.
D) cloning the putative enhancer into a plasmid and measuring the level of reporter gene expression in a prokaryotic cell.