Which of the following is a predicted consequence of kinetochores not achieving the correct level of tension from the mitotic spindle?
A)Sister chromatids will no longer be held together at their centromeres.
B)All chromosomes will migrate to one pole instead of to two opposite poles.
C)Mitosis will not progress beyond metaphase.
D)No prediction can be made.

Question

Quizplus · Accepted Answer

Kinetochores must achieve the correct level of tension from the mitotic spindle to ensure that chromosomes are properly aligned and segregated. If this tension is not achieved, the cell will not receive the signal to proceed from metaphase to anaphase, halting mitosis at metaphase. This is a checkpoint mechanism to prevent errors in chromosome segregation.

Which of the Following Is a Predicted Consequence of Kinetochores