The first step in base excision repair is
A)removal of a double-stranded fragment of damaged DNA.
B)nicking the backbone of one DNA strand.
C)recognizing and excising the incorrect base from a nucleotide.
D)removing extraneous groups such as methyl or oxygen added by mutagens.
E)replacing an A-T base pair with a C-G base pair.

Question

Quizplus · Accepted Answer

The first step in base excision repair involves recognizing and excising the incorrect or damaged base from a nucleotide. This is typically done by a specific glycosylase enzyme that identifies and removes the erroneous base, leaving behind an apurinic/apyrimidinic (AP) site.

The First Step in Base Excision Repair Is