Bradykinin is a nonapeptide, Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg.In addition to one mole of Arg, what peptides are present after hydrolysis of bradykinin with chymotrypsin?

Question

Quizplus · Accepted Answer

Chymotrypsin cleaves peptide bonds on the carboxyl side of aromatic amino acids like phenylalanine (Phe). Therefore, it will cleave bradykinin after the Phe residues, resulting in the peptides Arg-Pro-Pro-Gly-Phe and Ser-Pro-Phe.

Bradykinin Is a Nonapeptide, Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg