For drug molecules to readily cross the blood-brain barrier, they must be somewhat lipophilic (soluble in oil).

Question

Quizplus · Accepted Answer

Drug molecules that are lipophilic (oil-soluble) can more easily cross the blood-brain barrier because this barrier is made up of tightly packed cells that prevent most substances from passing through, but allows the passage of substances that can dissolve in the lipid bilayer of the cell membranes.

For Drug Molecules to Readily Cross the Blood-Brain Barrier, They