Antihistamines Should Be Used with Caution in Clients with Asthma

Antihistamines should be used with caution in clients with asthma or COPD.What is the rationale for this caution?

A) Anticholinergic effects of antihistamines can trigger angioedema.
B) Most people with asthma are allergic to antihistamines.
C) Antihistamines cause severe headache when given to clients with COPD or asthma.
D) Anticholinergic effects of antihistamines can trigger bronchospasm.