Why are antibodies to high-frequency antigens, such as cellano (k), rarely seen in patient samples?
A) Most persons are not antigenically stimulated to produce the antibody, because their red blood cells are negative for the antigen.
B) Most persons are not antigenically stimulated to produce the antibody, because their red blood cells are positive for the antigen.
C) Anti-k has low avidity.
D) Most reagent cells are heterozygous for cellano.

Question

Quizplus · Accepted Answer

Most individuals have the high-frequency antigen on their red blood cells, so they do not produce antibodies against it.

Why Are Antibodies to High-Frequency Antigens, Such as Cellano (K)