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Red Blood Cells That Phenotyped as [Le(a-B-)] Are Incubated with Plasma

Question 19

Multiple Choice

Red blood cells that phenotyped as [Le(a-b-) ] are incubated with plasma containing Lea substance. The red blood cells convert to the phenotype [Le(a+b-) ]. Whereas the same red blood cells incubated with saliva containing Lea substance do not convert. Why?


A) Glycoproteins are not absorbed onto red blood cell membranes.
B) Biochemically, Lewis substances in saliva are glycolipids.
C) Only Leb substance in saliva can convert phenotypes.
D) Other enzymes found in the saliva interfere with the conversion from Le(a-b-) to Le (a+b-) .

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