A woman undergoing a hysterectomy requires two units of blood. The antibody screen was negative. One unit was incompatible in the Coombs phase (2+), the other unit was compatible. Give a reason why this antibody was not detected in the antibody screen.

Question

Quizplus · Accepted Answer

The antibody was not detected in the antibody screen because it is likely directed against a low-frequency antigen, which may not be present on the screening cells used in the antibody screen.

A Woman Undergoing a Hysterectomy Requires Two Units of Blood