A Male Patient Was Seen in the Emergency Room with an Acute

A male patient was seen in the emergency room with an acute bleed. The recommendation from the blood supplier is to give O-positive RBCs as uncrossmatched blood. This patient has already been exposed to Rh-positive blood after a previous accident. What is a possible outcome?

A) The patient may have a hemolytic transfusion reaction from an allo-immunized anti-D.
B) Anti-D is not immunogenic, and the patient probably would not have formed an anti-D.
C) Anti-D is not hemolytic, and even with the circulating antibody there would be no danger to the patient.
D) The anti-D would activate complement, and a strong intravascular transfusion reaction would occur.