Only 5% of Kell-negative individuals will develop antibodies to Kell if exposed to the Kell antigen, whereas 50% to 70% of Rh(D)-negative individuals would produce antibodies to D upon exposure. What is the reason for this?
A) Difference in ABO type
B) Difference in immunogenicity
C) Phenotype
D) All of the above

Question

Quizplus · Accepted Answer

The difference in immunogenicity between the Kell and Rh(D) antigens explains why a higher percentage of Rh(D)-negative individuals develop antibodies compared to Kell-negative individuals. Rh(D) is more immunogenic than Kell.

Only 5% of Kell-Negative Individuals Will Develop Antibodies to Kell