Taking 1000 micrograms of amphetamine orally is equivalent to injecting _____ micrograms into the cerebrospinal fluid.
A)100
B)10
C)5
D)1

Question

Quizplus · Accepted Answer

Oral administration of amphetamine undergoes first-pass metabolism, reducing its bioavailability compared to direct injection into the cerebrospinal fluid, which bypasses this process. Therefore, a much smaller dose is needed when injected directly to achieve similar effects.

Taking 1000 Micrograms of Amphetamine Orally Is Equivalent to Injecting