The Basic Defect Responsible for Osteogenesis Imperfecta Is Produced by Different

The basic defect responsible for osteogenesis imperfecta is produced by different mutations affecting the genes that encode for type I collagen, resulting in:

A) lack of otic ossicles.
B) unilateral or bilateral aplasia or hypoplasia of clavicles.
C) overgrowth of cortical bone in the midline of the palate.
D) abnormally formed bones that fracture easily.