What causes closure of the foramen ovale at birth?
A) Higher pressure in the left atrium, which causes interatrial septum flaps to close
B) Rapid myocardial tissue growth stimulated by pregnancy hormones
C) A rise in fetal oxygen levels, which triggers growth of the epithelial lining
D) An increase in endothelial mucous production, which forms a plug
E) Migration of connective tissue from the right atrioventricular valve
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