Order: Hycamtin (topotecan HCl)1.5 mg/mIV daily for five days,repeat every 21 days. The label on the vial reads 4 mg,and the manufacturer's directions state: "Reconstitute each 4 mg with 4 mL of sterile water.Withdraw the dose and further dilute in 50 mL D₅W and infuse over 30 minutes." Calculate the rate of flow in milliliters per hour for a patient who weighs 92 kg and is 183 cm tall.

Question

Quizplus · Accepted Answer

The correct answer is A because 1.5 mg/m2 x 92 kg = 138 mg. 138 mg/4 mg/mL = 34.5 mL. 34.5 mL/50 mL = 0.69. 0.69 x 50 mL/30 min = 114 mL/h.

Order: Hycamtin (Topotecan HCl)1