Two proteins, Rag-1 and Rag-2, catalyze VDJ recombination.What is the likely outcome of a deletion of the Rag genes?

Question

Quizplus · Accepted Answer

Rag-1 and Rag-2 are essential for VDJ recombination, which is crucial for the development of diverse B and T cell receptors. A deletion of these genes would lead to an inability to produce functional B and T cells, resulting in severe combined immunodeficiency (SCID).

Two Proteins, Rag-1 and Rag-2, Catalyze VDJ Recombination