Genetic studies have found that Charcot-Marie-Tooth may be caused by a mutation in the gene Mitofusin-2 (MFN2), which causes mitochondria to form large clumps.In what area of a neuron are these clumps most likely to cause a problem?

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The axon is the part of the neuron responsible for transmitting signals over long distances. Mitochondrial dysfunction in the axon can disrupt energy supply and transport, leading to neurodegenerative issues like those seen in Charcot-Marie-Tooth disease.

Genetic Studies Have Found That Charcot-Marie-Tooth May Be Caused by a Mutation