People homozygous for the sickle-cell anemia allele develop a life threatening disease, while those homozygous for the normal allele are at the highest risk of dying from malaria.Carriers have some resistance to malaria, but do not develop sickle cell anemia.This is an example of ____

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Heterozygote advantage occurs when individuals with two different alleles (heterozygotes) have a higher fitness than individuals with two identical alleles (homozygotes). In this case, carriers of the sickle-cell allele (heterozygotes) have a survival advantage in malaria-prone regions.

People Homozygous for the Sickle-Cell Anemia Allele Develop a Life