A human autosomal recessive trait appears in 1 in 100 births.What percent of people are homozygous dominant for this trait?

Question

Quizplus · Accepted Answer

The frequency of the recessive allele (q) can be calculated using the square root of the incidence of the recessive phenotype (1/100 = 0.01), so q = √0.01 = 0.1. The frequency of the dominant allele (p) is 1 - q = 0.9. The frequency of homozygous dominant individuals (p^2) is (0.9)^2 = 0.81 or 81%.

A Human Autosomal Recessive Trait Appears in 1 in 100