You have been asked to design a synthetic DNA motif, able to bind transcriptional regulatory proteins.The location on this motif that you will design for protein binding is the
A)minor groove of the DNA double helix.
B)major groove of the DNA double helix.
C)phosphate backbone of the DNA double helix.
D)sugar backbone of the DNA double helix.

Question

Quizplus · Accepted Answer

The major groove of the DNA double helix is the primary site for protein binding because it provides more accessible chemical information and space for proteins to recognize specific DNA sequences.

You Have Been Asked to Design a Synthetic DNA Motif