The drug Taxol,or Paclitaxel,is used to treat patients with a variety of cancers,including breast,lung and ovarian cancers.The drug works by stabilizing microtubules,and preventing their disassembly.The goal of the drug is to prevent dividing cells from being able to complete mitosis.As a result,cancerous cells can no longer divide.In a cell treated with Taxol,at what stage of mitosis will the cells arrest?

Question

Quizplus · Accepted Answer

Taxol works by stabilizing microtubules which are responsible for organizing the spindle fibers that separate chromosomes during mitosis. By preventing disassembly of these microtubules, the cells cannot complete mitosis and divide. Therefore, the cells treated with Taxol will arrest at the stage prior to metaphase.

The Drug Taxol,or Paclitaxel,is Used to Treat Patients with a Variety