What disease played a key role in the Spanish conquest of Mexico?

Name: What disease played a key role in the Spanish conquest of Mexico?
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Smallpox played a key role in the Spanish conquest of Mexico as it was brought over by the Europeans and spread rapidly among the indigenous populations, who had no immunity to the disease. It is estimated that smallpox may have killed up to 90% of the native population, severely weakening their resistance to the Spanish invaders.

What Disease Played a Key Role in the Spanish Conquest