The most serious challenge to the United States in its expansion westward involved
A)major Amerindian problems.
B)equal status for new states entering the Union.
C)slavery.
D)territory claimed by other nations.
E)immigrants.

Question

Quizplus · Accepted Answer

The most serious challenge to the United States in its expansion westward was the issue of slavery, particularly how it would be addressed in new territories and states. This challenge led to significant national division and ultimately contributed to the outbreak of the Civil War.

The Most Serious Challenge to the United States in Its