How Do We Know That Chlorine Caused the Ozone Hole

How do we know that chlorine caused the ozone hole?

A) From laboratory experiments involving a replica of the atmosphere over Antarctica.
B) From the relationship between the release of chlorine by the Pinatubo volcano and the depletion of ozone over Antarctica a few months later.
C) From theories of the chemical destruction of ozone, coupled with computer calculations.
D) From measurements of the relationship between the experimental release of chlorine from the land surface in Antarctica, and the depletion of ozone that appeared in the atmosphere a few days later.
E) From measurements of chlorine monoxide and ozone in the Antarctic atmosphere as the sun reappeared in the spring.