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You Are Studying a New Phage That Infects H

Question 67

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You are studying a new phage that infects H. pylori. You have isolated two mutant strains of the phage, each producing a different plaque phenotype due to a specific mutation: rough (r) and big (b). You co-infect H. pylori with both strains by adding a mixture of phages to a culture of cells. You collect the cell lysate containing progeny phages, plate diluted phages on a lawn of H. pylori cells, and observe 970 rough plaques, 890 big plaques, 0 rough and big plaques, and 0 normal, wild-type plaques.
a. What is the recombination frequency between the r locus and the b locus?
b. How can you explain the results?

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a. Recombination frequency between the r...

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