How Is Colchicine, the Chemical Used in Preparing Karyotypes, Useful

How is colchicine, the chemical used in preparing karyotypes, useful for studying chromosomal mutations?

A) Colchicine prevents cells from entering anaphase, stalling them in metaphase with condensed chromosomes.
B) Colchicine induces chromosome condensation during interphase, which allows the visualization of interphase chromosomes.
C) Colchicine causes chromosomal breakage, leading to inversions and translocations that can be observed with a microscope.
D) Colchicine ruptures the cell membrane, allowing the spreading of cells on microscope slides.
E) Colchicine causes cells to exit the cell cycle, making the chromosome easier to visualize.