Most pedigrees showing the hypothetical human trait show the following characteristics:
• Females are affected twice as frequently as males.
• Affected fathers may have affected daughters but never affected sons.
• Half the children of affected mothers and normal fathers are affected.
What is the MOST likely mode of inheritance for this disorder?
A) autosomal recessive
B) autosomal dominant
C) X-linked recessive
D) X-linked dominant
E) Y-linked

Question

Most pedigrees showing the hypothetical human trait show the following characteristics: 
• Females are affected twice as frequently as males.
• Affected fathers may have affected daughters but never affected sons.
• Half the children of affected mothers and normal fathers are affected.
What is the MOST likely mode of inheritance for this disorder?
A) autosomal recessive
B) autosomal dominant
C) X-linked recessive
D) X-linked dominant
E) Y-linked

Quizplus · Accepted Answer

The trait is likely X-linked dominant because it affects females more frequently, affected fathers can pass it to daughters but not sons, and affected mothers have a 50% chance of passing it to their children.

Most Pedigrees Showing the Hypothetical Human Trait Show the Following