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Tony, Who Is Not Diseased, Has a Sister with Cystic

Question 53

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Tony, who is not diseased, has a sister with cystic fibrosis (CF). Neither of his parents has CF. Tony is expecting a child with Tina. Tina's family history is unknown. If the frequency of heterozygotes in the general population is 1/50, what is the probability that Tony and Tina's child will have CF? Explain each factor in your calculation.

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To calculate the probability that Tony a...

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