If the frequency of a recessive disease causing allele (q) is 0.005, what is the frequency of individuals with the disease in a population with an inbreeding coefficient of 0.25?

Question

Quizplus · Accepted Answer

The frequency of individuals with the disease is calculated using the formula q^2 + F*q*(1-q), where q is the allele frequency and F is the inbreeding coefficient. Substituting the given values: (0.005)^2 + 0.25*0.005*(1-0.005) = 0.000025 + 0.00125 = 0.001275, which is approximately 0.00127.

If the Frequency of a Recessive Disease Causing Allele (Q)