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In the late 1940s Edward Lewis discovered mutations in the Antennapedia gene that lead to legs developing on the head of a fly instead of antenna. These mutations are dominant and lead to ectopic expression of the Antennapedia gene.
-Certain mutations in the Antennapedia gene can lead to antenna developing in a mesothoracic segment where legs should have developed. What characteristics would you expect from this class of mutations? (Select all that apply.)
A) They are loss-of-function.
B) They are recessive.
C) They are gain-of-function.
D) They are dominant.
E) They result in ectopic Antennapedia expression.

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In the late 1940s Edward Lewis discovered mutations in the Antennapedia gene that lead to legs developing on the head of a fly instead of antenna. These mutations are dominant and lead to ectopic expression of the Antennapedia gene.
-Certain mutations in the Antennapedia gene can lead to antenna developing in a mesothoracic segment where legs should have developed. What characteristics would you expect from this class of mutations? (Select all that apply.)
A) They are loss-of-function.
B) They are recessive.
C) They are gain-of-function.
D) They are dominant.
E) They result in ectopic Antennapedia expression.

Quizplus · Accepted Answer

These mutations result in the loss of normal function, leading to antenna development where legs should be, and are typically recessive, as they require both alleles to be affected to show the phenotype.

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