How does histone acetylation affect chromatin structure?
A) neutralizes positive histone charges and results in more tightly packed chromatin
B) neutralizes negative histone charges and results in more tightly packed chromatin
C) increases positive histone charges and results in more tightly packed chromatin
D) neutralizes positive histone charges and results in more loosely packed chromatin
E) neutralizes negative histone charges and results in more loosely packed chromatin

Question

Quizplus · Accepted Answer

Histone acetylation neutralizes the positive charges on histones, reducing their affinity for the negatively charged DNA, leading to a more open chromatin structure and increased gene expression.

How Does Histone Acetylation Affect Chromatin Structure