Degradation of a eukaryotic mRNA is generally initiated by:
A) cleavage of the 5' end.
B) random cleavages throughout the mRNA strand.
C) shortening of the poly(A) tail.
D) recruitment of the chromosome-remodeling complex.
E) removal of the 5' cap.

Question

Quizplus · Accepted Answer

The degradation of eukaryotic mRNA typically begins with the shortening of the poly(A) tail, which destabilizes the mRNA and makes it more susceptible to further degradation processes.

Degradation of a Eukaryotic MRNA Is Generally Initiated By