A scientist created transgenic C. elegans worms that expressed a gene that made the worms glow green under fluorescent light. Then she injected double-stranded RNA complementary to this gene. Which of the following results was MOST likely to be seen?
A) The worms glowed green under fluorescent light.
B) The worms were not able to glow green under fluorescent light.
C) The injection of double-stranded RNA was lethal and the worms died.
D) The worms had an increased life span.
E) The CpG islands near the promoter of the gene became demethylated.

Question

Quizplus · Accepted Answer

Double-stranded RNA complementary to a gene can trigger RNA interference (RNAi), which leads to the degradation of the corresponding mRNA and inhibition of gene expression. In this case, the injection of double-stranded RNA complementary to the gene that made the worms glow green would likely result in the worms not being able to glow green under fluorescent light.

A Scientist Created Transgenic C