An auxotrophic E. coli strain requires adenine to grow because of a mutation in a gene for an adenine synthesis enzyme. The following shows part of the wild-type and mutant alleles of the gene, including the start codon. The bottom strand is the template for transcription. $$\begin{array} { c c }
\text { ade } 1 ^ { + } \text {wild-type allele } & \text { ade1 } ^ { - } \text {mutant allele } \
\text { 5'...TTATGGGCAAGATCCCA...3' } & \text { 5'....TTA TGGGCTAGATCCCA...3' } \
\text { 3'...AATACCCGTTCTAGGGT...5' } & \text { 3'...AATATGGGCTAGATCCCA...3' }
\end{array}$$
- How does this mutation change the mRNA, and how does it affect the enzyme?

Question

An auxotrophic E. coli strain requires adenine to grow because of a mutation in a gene for an adenine synthesis enzyme. The following shows part of the wild-type and mutant alleles of the gene, including the start codon. The bottom strand is the template for transcription. $$\begin{array} { c c } 
\text { ade } 1 ^ { + } \text {wild-type allele } & \text { ade1 } ^ { - } \text {mutant allele } \
\text { 5'...TTATGGGCAAGATCCCA...3' } &  \text { 5'....TTA TGGGCTAGATCCCA...3' } \
\text { 3'...AATACCCGTTCTAGGGT...5' } & \text { 3'...AATATGGGCTAGATCCCA...3' }
\end{array}$$
- How does this mutation change the mRNA, and how does it affect the enzyme?

Quizplus · Accepted Answer

The Answer of An auxotrophic E. coli strain requires adenine to grow because of a mutation in a gene for an adenine synthesis enzyme. The following shows part of the wild-type and mutant alleles of the gene, including the start codon. The bottom strand is the template for transcription. $$\begin{array} { c c } 
\text { ade } 1 ^ { + } \text {wild-type allele } & \text { ade1 } ^ { - } \text {mutant allele } \
\text { 5'...TTATGGGCAAGATCCCA...3' } &  \text { 5'....TTA TGGGCTAGATCCCA...3' } \
\text { 3'...AATACCCGTTCTAGGGT...5' } & \text { 3'...AATATGGGCTAGATCCCA...3' }
\end{array}$$
- How does this mutation change the mRNA, and how does it affect the enzyme?

An Auxotrophic E - How Does This Mutation Change the MRNA, and How