According to the endosymbiotic theory, the evolution of the cytoskeleton and a flexible plasma membrane preceded the evolution of mitochondria and chloroplasts.

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The endosymbiotic theory suggests that the development of a flexible plasma membrane and cytoskeleton allowed early eukaryotic cells to engulf prokaryotic cells, leading to the evolution of mitochondria and chloroplasts.

According to the Endosymbiotic Theory, the Evolution of the Cytoskeleton