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Hashimoto's Thyroiditis and Graves' Disease Are Autoimmune Diseases Involving the Thyroid

Question 74

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Hashimoto's thyroiditis and Graves' disease are autoimmune diseases involving the thyroid, but Hashimoto's results in hypothyroidism (low thyroid function), whereas Graves' results in hyperthyroidism (overactive thyroid). Both diseases are characterized by antithyroid antibodies. Discuss ways in which the autoimmune responses may produce the different outcomes.

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In Graves' disease, the antithyroid anti...

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