Huntington's disease is one of the few dominant genetic disorders that causes exaggerated involuntary jerking motions and progressive dementia. What area of the brain is primarily responsible for these symptoms?

Question

Quizplus · Accepted Answer

The basal nuclei (also known as basal ganglia) are primarily responsible for the symptoms of Huntington's disease, including exaggerated involuntary jerking motions (chorea) and progressive dementia. The basal nuclei are involved in the regulation of voluntary motor movements and procedural learning, and their dysfunction is a key factor in Huntington's disease pathology.

Huntington's Disease Is One of the Few Dominant Genetic Disorders